Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies.
Identifieur interne : 000964 ( 2020/Analysis ); précédent : 000963; suivant : 000965Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies.
Auteurs : Jianjun Gao [République populaire de Chine] ; Zhenxue Tian [République populaire de Chine] ; Xu Yang [République populaire de Chine]Source :
- Bioscience trends [ 1881-7823 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
- analogues et dérivés : Chloroquine.
- traitement médicamenteux : Infections à coronavirus, Pneumopathie virale.
- usage thérapeutique : Chloroquine.
- Chine, Essais cliniques comme sujet, Humains, Repositionnement des médicaments, Études multicentriques comme sujet.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- MESH :
- chemical , analogs & derivatives : Chloroquine.
- chemical , therapeutic use : Chloroquine.
- geographic : China.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- Betacoronavirus, Clinical Trials as Topic, Drug Repositioning, Humans, Multicenter Studies as Topic.
Abstract
The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People's Republic of China for treatment of COVID-19 infection in larger populations in the future.
DOI: 10.5582/bst.2020.01047
PubMed: 32074550
Affiliations:
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pubmed:32074550Le document en format XML
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<front><div type="abstract" xml:lang="en">The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People's Republic of China for treatment of COVID-19 infection in larger populations in the future.</div>
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